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Clinical Review Hormones / Cognition

Pregnenolone

Complete medical breakdown of Pregnenolone. Understand the pharmacokinetics, clinical indications, and how to safely integrate it into your protocol.

Clinical Summary

The 'mother hormone' synthesized directly from cholesterol. Modulates NMDA receptors for significant cognitive and memory support.

Pharmacokinetics & Bioavailability

When evaluating Pregnenolone, the most critical factor is its absorption rate. Currently, the clinical bioavailability score for this specific chemical form is rated at 6/10.

This high absorption rate ensures that the active compound reaches systemic circulation without causing excessive gastrointestinal distress, provided it is taken correctly.

Optimal Protocol Instructions

  • Best Time: Morning
  • Elemental Dose: 10mg - 30mg

Contraindications & Warnings

Do not take Pregnenolone without consulting your physician if you fall into any of the following categories.

History of seizures, hormone-dependent cancers

Verified Sourcing

Medical Board Pick

We have analyzed the raw material sourcing for Pregnenolone to ensure it meets strict clinical standards.

3rd Party Tested
Verified 6/10 Absorption
Exact 10mg - 30mg Yield
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