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Clinical Review Amino Acids

L-Citrulline

Complete medical breakdown of L-Citrulline. Understand the pharmacokinetics, clinical indications, and how to safely integrate it into your protocol.

Clinical Summary

Better absorbed than arginine hepatically; effectively increases endothelial nitric oxide (NO) production.

Pharmacokinetics & Bioavailability

When evaluating L-Citrulline, the most critical factor is its absorption rate. Currently, the clinical bioavailability score for this specific chemical form is rated at 9/10.

This high absorption rate ensures that the active compound reaches systemic circulation without causing excessive gastrointestinal distress, provided it is taken correctly.

Optimal Protocol Instructions

  • Best Time: 45 min before exercise
  • Elemental Dose: 3000mg - 6000mg

Contraindications & Warnings

Do not take L-Citrulline without consulting your physician if you fall into any of the following categories.

Erectile dysfunction medications (PDE5 inhibitors)

Verified Sourcing

Medical Board Pick

We have analyzed the raw material sourcing for L-Citrulline to ensure it meets strict clinical standards.

3rd Party Tested
Verified 9/10 Absorption
Exact 3000mg - 6000mg Yield
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